Investigating the role of the Wnt/ß-catenin pathway effector Tcf7l2, in colon adenoma organoids

• Main Author: Lee, Xin Er
• Other Authors: Ruedl Christiane
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2020
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/141793
• Institution: Nanyang Technological University

Tcf7l2 has been an interest of colon research due to its key role in Wnt/ß-catenin pathway and in colorectal cancer. With colon cancer being highly fatal in developed countries, it is crucial to find alternative treatments for colon cancer that are less toxic, more targeted and effective. Tcf7l2...