ACAP1 assembles into an unusual protein lattice for membrane deformation through multiple stages

• Main Authors: Chan, Chun, Pang, Xiaoyun, Zhang, Yan, Niu, Tongxin, Yang, Shengjiang, Zhao, Daohui, Li, Jian, Lu, Lanyuan, Hsu, Victor W., Zhou, Jian, Sun, Fei, Fan, Jun
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science::Biological sciences; Biochemical Simulations; Dimers
• 在線閱讀: https://hdl.handle.net/10356/142021

Studies on the Bin-Amphiphysin-Rvs (BAR) domain have advanced a fundamental understanding of how proteins deform membrane. We previously showed that a BAR domain in tandem with a Pleckstrin Homology (PH domain) underlies the assembly of ACAP1 (Arfgap with Coil-coil, Ankryin repeat, and PH domain I)...