SWPepNovo : an efficient de novo peptide sequencing tool for large-scale MS/MS spectra analysis

• Main Authors: Li, Chuang, Li, Kenli, Li, Keqin, Xie, Xianghui, Lin, Feng
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Computer science and engineering; Large-scale MS/MS Spectra Analysis; De Novo Peptide Sequencing
• Online Access: https://hdl.handle.net/10356/142187
• Institution: Nanyang Technological University

Tandem mass spectrometry (MS/MS)-based de novo peptide sequencing is a powerful method for high-throughput protein analysis. However, the explosively increasing size of MS/MS spectra dataset inevitably and exponentially raises the computational demand of existing de novo peptide sequencing methods,...