Structure determination of the IC3b protein from the human complement system and of proteins with immunological interest.

• Main Author: Lescar, Julien.
• Other Authors: School of Biological Sciences
• Format: Research Report
• Language: English
• Published: 2008
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology::Deoxyribonucleic acids
• Online Access: http://hdl.handle.net/10356/14224
• Institution: Nanyang Technological University

Integrins are cell surface receptors which play key roles in cell-cell, cell-extracellular matrix and cell-pathogen interactions. Moreover, their importance in tumor metastasis is increasingly appreciated. Integrins on circulating leukocytes are normally in a resting state of low adhesiveness, but c...