FAIM : an antagonist of Fas-killing and beyond

• Main Authors: Huo, Jianxin, Xu, Shengli, Lam, Kong-Peng
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; FAIM; B Cells
• Online Access: https://hdl.handle.net/10356/142251
• Institution: Nanyang Technological University

Fas Apoptosis Inhibitory Molecule (FAIM) is an anti-apoptotic protein that is up-regulated in B cell receptor (BCR)-activated B cells and confers upon them resistance to Fas-mediated cell death. Faim has two alternatively spliced isoforms, with the short isoform ubiquitously expressed in various tis...