Characterization of human transition zone reveals a putative progenitor-enriched niche of corneal endothelium

• Main Authors: Yam, Gary Hin-Fai, Seah, Xinyi, Nur Zahirah M. Yusoff, Setiawan, Melina, Wahlig, Stephen, Htoon, Hla Myint, Peh, Gary S. L., Kocaba, Viridiana, Mehta, Jodhbir Singh
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Materials; Corneal Endothelium; Posterior Limbus
• Online Access: https://hdl.handle.net/10356/142275
• Institution: Nanyang Technological University

The corneal endothelium regulates corneal hydration to maintain the transparency of cornea. Lacking regenerative capacity, corneal endothelial cell loss due to aging and diseases can lead to corneal edema and vision loss. There is limited information on the existence of corneal endothelial progenito...