Proposing drug fragments for dengue virus NS5 protein

• Main Authors: Alhossary, Amr, Awuni, Yaw, Kwoh, Chee Keong, Mu, Yuguang
• Other Authors: School of Computer Science and Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; Dengue; DENV NS5
• Online Access: https://hdl.handle.net/10356/142302
• Institution: Nanyang Technological University

Dengue fever is a febrile illness caused by Dengue Virus, which belongs to the Flaviviridae family. Among its proteome, the nonstructural protein 5 (NS5) is the biggest and most conserved. It has a primer-independent RNA-dependent RNA polymerase (RdRp) domain at its C-Terminus. Zou et al. studied th...