Factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study
Better understanding of atopic dermatitis' effect on quality of life could enhance current management and therapeutic strategies. Studies investigating factors related to the health-related quality of life (HRQOL) of children with atopic dermatitis and their caregivers are limited. This cross-s...
Saved in:
Main Authors: | , , , , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2020
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/142348 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
id |
sg-ntu-dr.10356-142348 |
---|---|
record_format |
dspace |
spelling |
sg-ntu-dr.10356-1423482020-11-01T05:21:00Z Factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study Xu, Xiaomeng van Galen, Louise Sandra Koh, Mark Jean Aan Bajpai, Ram Thng, Steven Yew, Yik Weng Ho, Valerie Pui Yoong Alagappan, Uma Järbrink, Krister Sven Ake Car, Josip Lee Kong Chian School of Medicine (LKCMedicine) Centre for Population Health Sciences Science::Medicine Atopic Dermatitis Caregivers Better understanding of atopic dermatitis' effect on quality of life could enhance current management and therapeutic strategies. Studies investigating factors related to the health-related quality of life (HRQOL) of children with atopic dermatitis and their caregivers are limited. This cross-sectional study included 559 children (<16 years) with atopic dermatitis and their caregivers. Disease severity was associated with infants' HRQOL (moderate: IRR: 1.42, 95% CI 1.20-1.67; severe: IRR: 1.72, 95% CI 1.32-2.24). Age and disease severity were associated with children's HRQOL (age: IRR: 0.99, 95% CI 0.98-1.00; moderate: IRR: 1.08, 95% CI 1.02-1.14). Quality of life subdomains itching/scratching, emotional distress and sleep disturbance were most reported and increased with higher disease severity. Both caregivers' mental and physical health were negatively affected by children's HRQOL (physical: IRR: 0.99, 95% CI 0.99-1.00; mental: IRR: 0.98, 95% CI 0.97-0.99). Sociodemographic characteristics (gender, ethnicity, educational attainment of carers, number of children) did not demonstrate significance in children's HRQOL model. In conclusion, current atopic dermatitis diagnostics and treatment have to be extended to the factors influencing both children' as their caregivers' quality of life and adapting management accordingly. Itching/scratching, emotional distress and sleep disturbance deserve attention. Sociodemographic characteristics in children's HRQOL models also merit attention in further research. ASTAR (Agency for Sci., Tech. and Research, S’pore) Published version 2020-06-19T05:31:58Z 2020-06-19T05:31:58Z 2019 Journal Article Xu, X., van Galen, L. S., Koh, M. J. A., Bajpai, R., Thng, S., Yew, Y. W., . . . Car, J. (2019). Factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study. Scientific Reports, 9(1), 15990-. doi:10.1038/s41598-019-51129-5 2045-2322 https://hdl.handle.net/10356/142348 10.1038/s41598-019-51129-5 31690745 2-s2.0-85074761847 1 9 en Scientific Reports © 2019 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Te images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. application/pdf |
institution |
Nanyang Technological University |
building |
NTU Library |
continent |
Asia |
country |
Singapore Singapore |
content_provider |
NTU Library |
collection |
DR-NTU |
language |
English |
topic |
Science::Medicine Atopic Dermatitis Caregivers |
spellingShingle |
Science::Medicine Atopic Dermatitis Caregivers Xu, Xiaomeng van Galen, Louise Sandra Koh, Mark Jean Aan Bajpai, Ram Thng, Steven Yew, Yik Weng Ho, Valerie Pui Yoong Alagappan, Uma Järbrink, Krister Sven Ake Car, Josip Factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study |
description |
Better understanding of atopic dermatitis' effect on quality of life could enhance current management and therapeutic strategies. Studies investigating factors related to the health-related quality of life (HRQOL) of children with atopic dermatitis and their caregivers are limited. This cross-sectional study included 559 children (<16 years) with atopic dermatitis and their caregivers. Disease severity was associated with infants' HRQOL (moderate: IRR: 1.42, 95% CI 1.20-1.67; severe: IRR: 1.72, 95% CI 1.32-2.24). Age and disease severity were associated with children's HRQOL (age: IRR: 0.99, 95% CI 0.98-1.00; moderate: IRR: 1.08, 95% CI 1.02-1.14). Quality of life subdomains itching/scratching, emotional distress and sleep disturbance were most reported and increased with higher disease severity. Both caregivers' mental and physical health were negatively affected by children's HRQOL (physical: IRR: 0.99, 95% CI 0.99-1.00; mental: IRR: 0.98, 95% CI 0.97-0.99). Sociodemographic characteristics (gender, ethnicity, educational attainment of carers, number of children) did not demonstrate significance in children's HRQOL model. In conclusion, current atopic dermatitis diagnostics and treatment have to be extended to the factors influencing both children' as their caregivers' quality of life and adapting management accordingly. Itching/scratching, emotional distress and sleep disturbance deserve attention. Sociodemographic characteristics in children's HRQOL models also merit attention in further research. |
author2 |
Lee Kong Chian School of Medicine (LKCMedicine) |
author_facet |
Lee Kong Chian School of Medicine (LKCMedicine) Xu, Xiaomeng van Galen, Louise Sandra Koh, Mark Jean Aan Bajpai, Ram Thng, Steven Yew, Yik Weng Ho, Valerie Pui Yoong Alagappan, Uma Järbrink, Krister Sven Ake Car, Josip |
format |
Article |
author |
Xu, Xiaomeng van Galen, Louise Sandra Koh, Mark Jean Aan Bajpai, Ram Thng, Steven Yew, Yik Weng Ho, Valerie Pui Yoong Alagappan, Uma Järbrink, Krister Sven Ake Car, Josip |
author_sort |
Xu, Xiaomeng |
title |
Factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study |
title_short |
Factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study |
title_full |
Factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study |
title_fullStr |
Factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study |
title_full_unstemmed |
Factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study |
title_sort |
factors influencing quality of life in children with atopic dermatitis and their caregivers : a cross-sectional study |
publishDate |
2020 |
url |
https://hdl.handle.net/10356/142348 |
_version_ |
1683493751669915648 |