The dual interactions of p53 with MDM2 and p300 : implications for the design of MDM2 inhibitors

Proteins that limit the activity of the tumour suppressor protein p53 are increasingly being targeted for inhibition in a variety of cancers. In addition to the development of small molecules, there has been interest in developing constrained (stapled) peptide inhibitors. A stapled peptide ALRN_6924...

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Bibliographic Details
Main Authors: Kannan, Srinivasaraghavan, Partridge, Anthony William, Lane, David P., Verma, Chandra Shekhar
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/142381
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Institution: Nanyang Technological University
Language: English