Direct quantification of the translocation activities of Saccharomyces cerevisiae Pif1 helicase

• Main Authors: Lu, Chen, Le, Shimin, Chen, Jin, Byrd, Alicia K., Rhodes, Daniela, Raney, Kevin D., Yan, Jie
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; Saccharomyces Cerevisiae Pif1 (ScPif1); ATP-dependent DNA Helicase
• Online Access: https://hdl.handle.net/10356/142460
• Institution: Nanyang Technological University

Saccharomyces cerevisiae Pif1 (ScPif1) is known as an ATP-dependent DNA helicase that plays critical roles in a number of important biological processes such as DNA replication, telomere maintenance and genome stability maintenance. Besides its DNA helicase activity, ScPif1 is also known as a single...