Effects of miR-219/miR-338 on microglia and astrocyte behaviors and astrocyte-oligodendrocyte precursor cell interactions

• Main Authors: Nguyen, Lan Huong, Ong, William, Wang, Kai, Wang, Mingfeng, Nizetic, Dean, Chew, Sing Yian
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Chemical engineering; Central Nervous System; Electrospinning
• Online Access: https://hdl.handle.net/10356/142526
• Institution: Nanyang Technological University

MiR-219 and miR-338 (miR-219/miR-338) are oligodendrocyte-specific microRNAs. The overexpression of these miRs in oligodendrocyte precursor cells promotes their differentiation and maturation into oligodendrocytes, which may enhance axonal remyelination after nerve injuries in the central nervous sy...