Antibodies and venom peptides : new modalities for ion channels

• Main Authors: Wulff, Heike, Christophersen, Palle, Colussi, Paul, Chandy, Kanianthara George, Yarov-Yarovoy, Vladimir
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Antibodies; Venom Peptides
• Online Access: https://hdl.handle.net/10356/143155
• Institution: Nanyang Technological University

Ion channels play fundamental roles in both excitable and non-excitable tissues and therefore constitute attractive drug targets for myriad neurological, cardiovascular and metabolic diseases as well as for cancer and immunomodulation. However, achieving selectivity for specific ion channel subtypes...