Spatiotemporal-controlled reporter for cell-surface proteolytic enzyme activity visualization

• Main Authors: Cheong, Haolun, Kim, Jisu, Mu, Jing, Zhang, Wenmin, Li, Juan, Yang, HuangHao, Xing, Bengang
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Biosensors; Enzymes
• Online Access: https://hdl.handle.net/10356/143223
• Institution: Nanyang Technological University

Live‐cell imaging of cell‐surface‐associated proteolytic enzymes is crucial to understand their biological roles and functions in both physiological and pathological processes. However, the complexity of the cell membrane environment increases difficulties in specifically investigating targeted prot...