Multiplex surface-enhanced Raman scattering identification and quantification of urine metabolites in patient samples within 30 min

• Main Authors: Kao, Ya-Chuan, Han, Xuemei, Lee, Yih Hong, Lee, Hiang Kwee, Phan-Quang, Gia Chuong, Lay, Chee Leng, Sim, Howard Yi Fan, Phua, Vanessa Jing Xin, Ng, Li Shiuan, Ku, Chee Wai, Tan, Thiam Chye, Phang, In Yee, Tan, Nguan Soon, Ling, Xing Yi
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Physics; Surface-enhanced Raman Spectroscopy (SERS); Superhydrophobic SERS Platform
• Online Access: https://hdl.handle.net/10356/143412
• Institution: Nanyang Technological University

Successful translation of laboratory-based surface-enhanced Raman scattering (SERS) platforms to clinical applications requires multiplex and ultratrace detection of small biomarker molecules from a complex biofluid. However, these biomarker molecules generally exhibit low Raman scattering cross sec...