A new approach to design artificial 3D microniches with combined chemical, topographical, and rheological cues

• Main Authors: Stoecklin, Celine, Yue, Zhang, Chen, Wilhelm W., de Mets, Richard, Fong, Eileen, Studer, Vincent, Viasnoff, Virgile
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Materials; 3D Cell Culture; Biomimetic Materials
• Online Access: https://hdl.handle.net/10356/143611
• Institution: Nanyang Technological University

The in vitro methods to recapitulate environmental cues around cells are usually optimized to test a specific property of the environment (biochemical nature or the stiffness of the extracellular matrix (ECM), or nanotopography) for its capability to induce defined cell behaviors (lineage commitment...