Multicomponent supported membrane microarray for monitoring spatially resolved cellular signaling reactions

• Main Authors: Biswas, Kabir H., Chen, Zhongwen, Dubey, Alok Kumar, Oh, Dongmyung, Groves, Jay T.
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Materials; Cell Signaling; Lipid Exchange
• Online Access: https://hdl.handle.net/10356/143720
• Institution: Nanyang Technological University

Cells sense biochemical as well as mechanical signals from their microenvironment by engaging multiple receptors. In many cases, multiple receptors operate in concert, and it can be misleading to attempt to isolate a single ligand–receptor interaction. Supported lipid membranes are employed to recon...