An aromatic cluster in Lysinibacillus sphaericus BinB involved in toxicity and proper in-membrane folding

• المؤلفون الرئيسيون: Chooduang, Sivadatch, Surya, Wahyu, Torres, Jaume, Boonserm, Panadda
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Biological sciences::Biochemistry; Pore-forming Toxin; Lysinibacillus Sphaericus Binary Toxin
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/143822

The binary toxin from Lysinibacillus sphaericus has been successfully used for controlling mosquito-transmitted diseases. Based on structural alignments with other toxins, an aromatic cluster in the C-terminal domain of BinB (termed here BC) has been proposed to be important for toxicity. We tested...