An aromatic cluster in Lysinibacillus sphaericus BinB involved in toxicity and proper in-membrane folding

• Main Authors: Chooduang, Sivadatch, Surya, Wahyu, Torres, Jaume, Boonserm, Panadda
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science::Biological sciences::Biochemistry; Pore-forming Toxin; Lysinibacillus Sphaericus Binary Toxin
• 在線閱讀: https://hdl.handle.net/10356/143822
• 機構: Nanyang Technological University

The binary toxin from Lysinibacillus sphaericus has been successfully used for controlling mosquito-transmitted diseases. Based on structural alignments with other toxins, an aromatic cluster in the C-terminal domain of BinB (termed here BC) has been proposed to be important for toxicity. We tested...