Identification of clathrin proteins by incorporating hyperparameter optimization in deep learning and PSSM profiles

• Main Authors: Le, Nguyen Quoc Khanh, Huynh, Tuan-Tu, Yapp, Edward Kien Yee, Yeh, Hui-Yuan
• Other Authors: School of Humanities
• Format: Article
• Language: English
• Published: 2020
• Subjects: Humanities::General; Clathrin Coated Pits; Convolutional Neural Network
• Online Access: https://hdl.handle.net/10356/143870
• Institution: Nanyang Technological University

Background and Objectives: Clathrin is an adaptor protein that serves as the principal element of the vesicle-coating complex and is important for the membrane cleavage to dispense the invaginated vesicle from the plasma membrane. The functional loss of clathrins has been tied to a lot of human dise...