Lineage-specific exosomes could override extracellular matrix mediated human mesenchymal stem cell differentiation

• Main Authors: Narayanan, Karthikeyan, Kumar, Sundramurthy, Padmanabhan, Parasuraman, Gulyas, Balazs, Wan, Andrew C. A., Rajendran, Vazhaikkurichi M.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Extracellular Matrix; Exosomes
• Online Access: https://hdl.handle.net/10356/143959
• Institution: Nanyang Technological University

Lineage specification is an essential process in stem cell fate, tissue homeostasis and development. Microenvironmental cues provide direct and selective extrinsic signals to regulate lineage specification of stem cells. Microenvironmental milieu consists of two essential components, one being extra...