Solid-state NMR 13C, 15N assignments of human histone H3 in the nucleosome core particle

• المؤلفون الرئيسيون: Shi, Xiangyan, Prasanna, Chinmayi, Pervushin, Konstantin, Nordenskiöld, Lars
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Biological sciences; Solid-state NMR; Histone
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/144001
• المؤسسة: Nanyang Technological University

Nucleosome core particle (NCP), the basic unit of chromatin in eukaryotic cells, consists of ~ 147 bp DNA wrapped around a histone octamer (HO) formed by two H2A–H2B dimers and one (H3–H4)2 tetramer. Histones undergo various post-translational modifications (PTMs), which regulates genomic activities...