Dynamic networks observed in the nucleosome core particles couple the histone globular domains with DNA

The dynamics of eukaryotic nucleosomes are essential in gene activity and well regulated by various factors. Here, we elucidated the internal dynamics at multiple timescales for the human histones hH3 and hH4 in the Widom 601 nucleosome core particles (NCP), suggesting that four dynamic networks are...

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Bibliographic Details
Main Authors: Shi, Xiangyan, Prasanna, Chinmayi, Soman, Aghil, Pervushin, Konstantin, Nordenskiöld, Lars
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/145367
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Institution: Nanyang Technological University
Language: English