Mechanism and application of oxygen-independent photocleavage of blebbistatin as a blue or near-infrared light-gated hydroxyl radical photocage

• المؤلفون الرئيسيون: Li, Ming-De, Wong, Nai-Kei, Huang, Guanheng, Chen, Xuebo, Yang, Dan, Phillips, David Lee
• مؤلفون آخرون: Asian Spectroscopy Conference 2020
• التنسيق: Conference or Workshop Item
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Chemistry; Photocage; Blebbistatin
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/144190

Development of versatile, chemically tunable photocages for photoactivated chemotherapy (PACT) represents an excellent opportunity to address the technical drawbacks of conventional photodynamic therapy (PDT) whose oxygen-dependent nature renders it inadequate in certain therapy contexts such as hyp...