Spatiotemporal coordination of FGF and Shh signaling underlies the specification of myoblasts in the zebrafish embryo

• Main Authors: Yin, Jianmin, Lee, Raymond, Ono, Yosuke, Ingham, Philip William, Saunders, Timothy E.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; Adaxial Cells; Fast Muscle Fibers
• Online Access: https://hdl.handle.net/10356/144211
• Institution: Nanyang Technological University

Somitic cells give rise to a variety of cell types in response to Hh, BMP, and FGF signaling. Cell position within the developing zebrafish somite is highly dynamic: how, when, and where these signals specify cell fate is largely unknown. Combining four-dimensional imaging with pathway perturbations...