NIR “matchbox size” spectrometer can quantify and detect malaria infection in Plasmodium falciparum infected red blood cells

NIR “matchbox size” spectrometer can quantify and detect malaria infection in Plasmodium falciparum infected red blood cells

New point-of-care diagnostic approaches for malaria that are highly sensitive, portable and affordable are urgently needed to meet the World Health Organization’s objective of reducing malaria cases and related life losses by at least 90% globally on or before 2030.1 In this study, an ultra-cheap ma...

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Bibliographic Details
Main Authors: Adegoke, John A., Kochan, Kamila, Heraud, Philip, Wood, Bayden R.
Other Authors: Asian Spectroscopy Conference 2020
Format: Conference or Workshop Item
Language:English
Published: 2020
Subjects:
Science::Chemistry
Near Infrared Spectroscopy
Chemometrics
Online Access:https://hdl.handle.net/10356/144309
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Institution: Nanyang Technological University
Language: English
Description
Summary:New point-of-care diagnostic approaches for malaria that are highly sensitive, portable and affordable are urgently needed to meet the World Health Organization’s objective of reducing malaria cases and related life losses by at least 90% globally on or before 2030.1 In this study, an ultra-cheap matchbox size near-infrared (NIR) spectrophotometer was used for the first time to detect and quantify malaria infection in vitro from isolated dried red blood cells using a fingerpick volume (15 μl) of blood, down to 0.0001% parasitemia.

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