An evaluation of inhaled antibiotic liposome versus antibiotic nanoplex in controlling infection in bronchiectasis

• Main Authors: Tran, The-Thien, Yu, Hong, Vidaillac, Celine, Lim, Albert Y. H., Abisheganaden, John A., Chotirmall, Sanjay Haresh, Hadinoto, Kunn
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Chemical engineering; Ciprofloxacin; Liposomes
• Online Access: https://hdl.handle.net/10356/144358
• Institution: Nanyang Technological University

Inhaled antibiotic nanoparticles have emerged as an effective strategy to control infection in bronchiectasis lung owed to their mucus-penetrating ability. Using ciprofloxacin (CIP) as the model antibiotic, we evaluated dry powder inhaler (DPI) formulations of two classes of antibiotic nanoparticles...