A simple strategy to enhance the in vivo wound-healing activity of curcumin in the form of self-assembled nanoparticle complex of curcumin and oligochitosan

• Main Authors: Nguyen, Minh-Hiep, Lee, Suen Ern, Tran, The-Thien, Bui, Chi-Bao, Nguyen, Thi-Huynh-Nga, Vu, Ngoc-Bich-Dao, Tran, Thi-Thuy, Nguyen, Trong-Hoanh-Phong, Nguyen, Thi-Thu, Hadinoto, Kunn
• 其他作者: School of Chemical and Biomedical Engineering
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Engineering::Chemical engineering; Wound Healing Agent; Curcumin
• 在線閱讀: https://hdl.handle.net/10356/144568

While the wound healing activity of curcumin (CUR) has been well-established, its clinical effectiveness remains limited due to the inherently low aqueous CUR solubility, resulting in suboptimal CUR exposure in the wound sites. Previously, we developed high-payload amorphous nanoparticle complex (or...