Apolipoprotein E4 polymorphism and outcomes from traumatic brain injury : a living systematic review and meta-analysis

• Main Authors: McFadyen, Charles A., Zeiler, Frederick A., Newcombe, Virginia, Synnot, Anneliese, Steyerberg, Ewout, Gruen, Russel Lindsay, Rosand, Jonathan, Palotie, Aarno, Maas, Andrew I. R., Menon, David K.
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2020
• 主題: Science::Medicine; Genetics; Living Systematic Reviews
• 在線閱讀: https://hdl.handle.net/10356/144650
• 機構: Nanyang Technological University

The mortality of traumatic brain injury (TBI) has been largely static despite advances in monitoring and imaging techniques. Substantial variance exists in outcome, not fully accounted for by baseline characteristics or injury severity, and genetic factors likely play a role in this variance. The ai...