Computational structure analysis of coronavirus ion channels thermodynamic stability with evolutionary divergence

• المؤلف الرئيسي: Ng, Linus Kah Way
• مؤلفون آخرون: Konstantin Pervushin
• التنسيق: Final Year Project
• اللغة: English
• منشور في: Nanyang Technological University 2020
• الموضوعات: Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/144651

Pandemic caused by novel SARS-CoV-2 has brought about much change in how society works. With little understanding of the virus, treatments are far and few between. Research has uncovered major contribution by viral ion channel proteins, mainly 3a and E, to viral virulence. Thus, inhibition of these...