Computational structure analysis of coronavirus ion channels thermodynamic stability with evolutionary divergence

• Main Author: Ng, Linus Kah Way
• Other Authors: Konstantin Pervushin
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2020
• Subjects: Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/144651
• Institution: Nanyang Technological University

Pandemic caused by novel SARS-CoV-2 has brought about much change in how society works. With little understanding of the virus, treatments are far and few between. Research has uncovered major contribution by viral ion channel proteins, mainly 3a and E, to viral virulence. Thus, inhibition of these...