Exploring extracellular vesicles biogenesis in hypothalamic cells through a heavy isotope pulse/trace proteomic approach

• المؤلفون الرئيسيون: Tan, Chee Fan, Teo, Hui San, Park, Jung Eun, Dutta, Bamaprasad, Tse, Shun Wilford, Leow, Melvin Khee-Shing, Wahli, Walter, Sze, Siu Kwan
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Medicine; Extracellular Vesicles; Extracellular Vesicles Biogenesis
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/144746
• المؤسسة: Nanyang Technological University

Studies have shown that the process of extracellular vesicles (EVs) secretion and lysosome status are linked. When the lysosome is under stress, the cells would secrete more EVs to maintain cellular homeostasis. However, the process that governs lysosomal activity and EVs secretion remains poorly de...