Deeper investigation into the utility of functional class scoring in missing protein prediction from proteomics data

• Main Authors: Zhao, Yaxing, Sue, Andrew Chi-Hau, Goh, Wilson Wen Bin
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; Proteomics; Functional Class Scoring
• Online Access: https://hdl.handle.net/10356/144754
• Institution: Nanyang Technological University

Functional Class Scoring (FCS) is a network-based approach previously demonstrated to be powerful in missing protein prediction (MPP). We update its performance evaluation using data derived from new proteomics technology (SWATH) and also checked for reproducibility using two independent datasets pr...