Diastereoselective intramolecular hydride transfer under brønsted acid catalysis

• Main Authors: Wang, Bin, Gandamana, Dhika Aditya, Gagosz, Fabien, Chiba, Shunsuke
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Chemistry; Substituents; Alcohols
• Online Access: https://hdl.handle.net/10356/144900
• Institution: Nanyang Technological University

A diastereoselective hydride transfer process has been developed under Brønsted acid-catalyzed reaction conditions using methyl ethers or acetals as hydride donors and tertiary alcohols or alkenes as precursors of carbocation. The method enables construction of complex molecules having multiple ster...