Identification of a novel p52-regulated long noncoding RNA in multiple myeloma

• المؤلف الرئيسي: Ang, Daniel Aron
• مؤلفون آخرون: Li Yinghui
• التنسيق: Thesis-Master by Research
• اللغة: English
• منشور في: Nanyang Technological University 2020
• الموضوعات: Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/145120
• المؤسسة: Nanyang Technological University

Multiple myeloma (MM) is a monoclonal plasma cell neoplasm accounting for 20 % of all blood-associated cancers. Mutations in factors of the non-canonical NF-kB (ncNF-kB) pathway have been associated with MM. Here we show that MM mutant cell lines display constitutive ncNF-kB pathway activation and t...