Variable computed tomography appearances of COVID-19

The coronavirus disease 2019 (COVID-19) is typically diagnosed by specific assays that detect viral nucleic acid from the upper respiratory tract; however, this may miss infections involving only the lower airways. Computed tomography (CT) has been described as a diagnostic modality in the COVID-19...

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Main Authors: Lim, Zhan Ye, Khoo, Hau Wei, Hui, Terrence Chi Hong, Kok, Shawn Shi Xian, Kwan, Kenneth Eng Ling, Young, Barnaby Edward, Tan, Cher Heng, Kaw, Gregory Jon Leng
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2020
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Online Access:https://hdl.handle.net/10356/145196
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1451962023-03-05T16:47:27Z Variable computed tomography appearances of COVID-19 Lim, Zhan Ye Khoo, Hau Wei Hui, Terrence Chi Hong Kok, Shawn Shi Xian Kwan, Kenneth Eng Ling Young, Barnaby Edward Tan, Cher Heng Kaw, Gregory Jon Leng Lee Kong Chian School of Medicine (LKCMedicine) Science::Medicine Computed Tomography Coronavirus Disease The coronavirus disease 2019 (COVID-19) is typically diagnosed by specific assays that detect viral nucleic acid from the upper respiratory tract; however, this may miss infections involving only the lower airways. Computed tomography (CT) has been described as a diagnostic modality in the COVID-19 diagnosis and treatment plan. We present a case series with virologically confirmed COVID-19 pneumonia. Variable CT features were observed: consolidation with ground-glass opacities, ground-glass opacities with subpleural reticular bands, and an anterior-posterior gradient of lung abnormalities resembling that of acute respiratory distress syndrome. Evolution of CT findings was observed in one patient, where there was interval resolution of bilateral lung consolidation with development of bronchiolectasis and subpleural fibrotic bands. While sensitive for detecting lung parenchymal abnormalities in COVID-19 pneumonia, the use of CT for initial diagnosis is discouraged and should be reserved for specific clinical indications. Interpretation of chest CT findings should be correlated with duration of symptoms to better determine the disease stage and aid in patient management. Published version 2020-12-15T02:54:30Z 2020-12-15T02:54:30Z 2020 Journal Article Lim, Z. Y., Khoo, H. W., Hui, T. C. H., Kok, S. S. X., Kwan, K. E. L., Young, B. E., . . . Kaw, G. J. L. (2020). Variable computed tomography appearances of COVID-19. Singapore Medical Journal, 61(7), 387-391. doi:10.11622/smedj.2020066 0037-5675 https://hdl.handle.net/10356/145196 10.11622/smedj.2020066 32312025 7 61 387 391 en Singapore Medical Journal © 2020 Singapore Medical Association. All rights reserved. This paper was published in Singapore Medical Journal and is made available with permission of Singapore Medical Association. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
Computed Tomography
Coronavirus Disease
spellingShingle Science::Medicine
Computed Tomography
Coronavirus Disease
Lim, Zhan Ye
Khoo, Hau Wei
Hui, Terrence Chi Hong
Kok, Shawn Shi Xian
Kwan, Kenneth Eng Ling
Young, Barnaby Edward
Tan, Cher Heng
Kaw, Gregory Jon Leng
Variable computed tomography appearances of COVID-19
description The coronavirus disease 2019 (COVID-19) is typically diagnosed by specific assays that detect viral nucleic acid from the upper respiratory tract; however, this may miss infections involving only the lower airways. Computed tomography (CT) has been described as a diagnostic modality in the COVID-19 diagnosis and treatment plan. We present a case series with virologically confirmed COVID-19 pneumonia. Variable CT features were observed: consolidation with ground-glass opacities, ground-glass opacities with subpleural reticular bands, and an anterior-posterior gradient of lung abnormalities resembling that of acute respiratory distress syndrome. Evolution of CT findings was observed in one patient, where there was interval resolution of bilateral lung consolidation with development of bronchiolectasis and subpleural fibrotic bands. While sensitive for detecting lung parenchymal abnormalities in COVID-19 pneumonia, the use of CT for initial diagnosis is discouraged and should be reserved for specific clinical indications. Interpretation of chest CT findings should be correlated with duration of symptoms to better determine the disease stage and aid in patient management.
author2 Lee Kong Chian School of Medicine (LKCMedicine)
author_facet Lee Kong Chian School of Medicine (LKCMedicine)
Lim, Zhan Ye
Khoo, Hau Wei
Hui, Terrence Chi Hong
Kok, Shawn Shi Xian
Kwan, Kenneth Eng Ling
Young, Barnaby Edward
Tan, Cher Heng
Kaw, Gregory Jon Leng
format Article
author Lim, Zhan Ye
Khoo, Hau Wei
Hui, Terrence Chi Hong
Kok, Shawn Shi Xian
Kwan, Kenneth Eng Ling
Young, Barnaby Edward
Tan, Cher Heng
Kaw, Gregory Jon Leng
author_sort Lim, Zhan Ye
title Variable computed tomography appearances of COVID-19
title_short Variable computed tomography appearances of COVID-19
title_full Variable computed tomography appearances of COVID-19
title_fullStr Variable computed tomography appearances of COVID-19
title_full_unstemmed Variable computed tomography appearances of COVID-19
title_sort variable computed tomography appearances of covid-19
publishDate 2020
url https://hdl.handle.net/10356/145196
_version_ 1759858171276427264