Single cell hydrodynamic stretching and microsieve filtration reveal genetic, phenotypic and treatment-related links to cellular deformability

Deformability is shown to correlate with the invasiveness and metastasis of cancer cells. Recent studies suggest epithelial-to-mesenchymal transition (EMT) might enable cancer metastasis. However, the correlation of EMT with cancer cell deformability has not been well elucidated. Cellular deformabil...

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Bibliographic Details
Main Authors: Li, Fenfang, Cima, Igor, Vo, Jess Honganh, Tan, Min-Han, Ohl, Claus-Dieter
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://hdl.handle.net/10356/145259
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Institution: Nanyang Technological University
Language: English