Peptide-protein coassembling matrices as a biomimetic 3D model of ovarian cancer

• Main Authors: Hedegaard, Clara Louise, Redondo-Gómez, Carlos, Tan, Bee Yi, Ng, Kee Woei, Loessner, Daniela, Mata, Alvaro
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Bioengineering; Biomimetics; Cell Culture
• Online Access: https://hdl.handle.net/10356/145362
• Institution: Nanyang Technological University

Bioengineered three-dimensional (3D) matrices expand our experimental repertoire to study tumor growth and progression in a biologically relevant, yet controlled, manner. Here, we used peptide amphiphiles (PAs) to coassemble with and organize extracellular matrix (ECM) proteins producing tunable 3D...