Nanoparticle elasticity regulates phagocytosis and cancer cell uptake

• Main Authors: Hui, Yue, Yi, Xin, Wibowo, David, Yang, Guangze, Middelberg, Anton P. J., Gao, Huajian, Zhao, Chun-Xia
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Engineering::Bioengineering; Antigen-antibody Reactions; Biomechanics
• Online Access: https://hdl.handle.net/10356/145409
• Institution: Nanyang Technological University

The ability of cells to sense external mechanical cues is essential for their adaptation to the surrounding microenvironment. However, how nanoparticle mechanical properties affect cell-nanoparticle interactions remains largely unknown. Here, we synthesized a library of silica nanocapsules (SNCs) wi...