Investigating super-enhancer-associated chromatin interactions at the HOXA9-MEIS1 oncogene signalling axis in myeloid leukaemia

Myeloid leukaemia is a form of blood cancer that is characterised by a block in haematopoietic stem cell differentiation and uncontrolled cell proliferation. HOXA9 and MEIS1 are two commonly overexpressed oncogenes that are associated with poor prognoses in myeloid leukaemia patients. However, our u...

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Bibliographic Details
Main Author: Wang, Benny Zheng Jie
Other Authors: Melissa Jane Fullwood
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2020
Subjects:
Online Access:https://hdl.handle.net/10356/145566
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Institution: Nanyang Technological University
Language: English