Self-assembling β-glucan nanomedicine for the delivery of siRNA

• Main Authors: Lee, Kyungwoo, Min, Daejin, Choi, Yonghyun, Yoon, Semi, Jang, Jaehee, Hwang, Jangsun, Jeon, Hojeong, Cho, Yong Woo, Choi, Jonghoon
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Beta-glucan; Self-assembly
• Online Access: https://hdl.handle.net/10356/145582
• Institution: Nanyang Technological University

We aimed to design and manufacture a transporter capable of delivering small interfering RNAs (siRNAs) into the skin without causing any damage. β-glucans are unique chiral polysaccharides with well-defined immunological properties and supramolecular wrapping ability. However, the chiral properties...