Emerging roles of downstream of kinase 3 in cell signaling

• Main Authors: Loh, Jia Tong, Teo, Joey Kay Hui, Lim, Hong-Hwa, Lam, Kong-Peng
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Biological sciences; Dok-3; Adaptor
• Online Access: https://hdl.handle.net/10356/145628
• Institution: Nanyang Technological University

Downstream of kinase (Dok) 3 is a member of the Dok family of adaptor proteins known to regulate signaling pathways downstream of various immunoreceptors. As Dok-3 lacks intrinsic catalytic activity, it functions primarily as a molecular scaffold to facilitate the nucleation of protein complexes in...