Mitochondrial dysfunction and Parkinson’s disease — near-infrared photobiomodulation as a potential therapeutic strategy

• Main Authors: Foo, Aaron Song Chuan, Soong, Tuck Wah, Yeo, Tseng Tsai, Lim, Kah-Leong
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Parkinson’s Disease; Mitochondria Dysfunction
• Online Access: https://hdl.handle.net/10356/145660
• Institution: Nanyang Technological University

As the main driver of energy production in eukaryotes, mitochondria are invariably implicated in disorders of cellular bioenergetics. Given that dopaminergic neurons affected in Parkinson’s disease (PD) are particularly susceptible to energy fluctuations by their high basal energy demand, it is not...