Inclusion of cross-linked elastin in gelatin/PEG hydrogels favourably influences fibroblast phenotype

• Main Authors: Cao, Ye, Lee, Bae Hoon, Irvine, Scott Alexander, Wong, Yee Shan, Peled, Havazelet Bianco, Venkatraman, Subramanian
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Materials; Polyethylene Glycol Hydrogel; Myofibroblast
• Online Access: https://hdl.handle.net/10356/145937
• Institution: Nanyang Technological University

The capacity of a biomaterial to innately modulate cell behavior while meeting the mechanical property requirements of the implant is a much sought-after goal within bioengineering. Here we covalently incorporate soluble elastin into a gelatin–poly (ethylene glycol) (PEG) hydrogel for three-dimensio...