Facile mixing of phospholipids promotes self-assembly of low-molecular-weight biodegradable block co-polymers into functional vesicular architectures

• Main Authors: Khan, Amit Kumar, Ho, James Chin Shing, Roy, Susmita, Liedberg, Bo, Nallani, Madhavan
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Materials; Self-assembly; Polymer-lipid Hybrid
• Online Access: https://hdl.handle.net/10356/145938
• Institution: Nanyang Technological University

In this work, we have used low-molecular-weight (PEG12-b-PCL6, PEG12-b-PCL9 or PEG16-b-PLA38; MW, 1.25–3.45 kDa) biodegradable block co-polymers to construct nano- and micron-scaled hybrid (polymer/lipid) vesicles, by solvent dispersion and electroformation methods, respectively. The hybrid vesicles...