Influence of high intensity focused ultrasound on the microstructure and c-di-GMP signaling of pseudomonas aeruginosa biofilms

• Main Authors: Bharatula, Lakshmi Deepika, Marsili, Enrico, Rice, Scott A., Kwan, James J.
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences; Pseudomonas Aeruginosa; Biofilm
• Online Access: https://hdl.handle.net/10356/145967
• Institution: Nanyang Technological University

Bacterial biofilms are typically more tolerant to antimicrobials compared to bacteria in the planktonic phase and therefore require alternative treatment approaches. Mechanical biofilm disruption from ultrasound may be such an alternative by circumventing rapid biofilm adaptation to antimicrobial ag...