Vimentin protects differentiating stem cells from stress

• Main Authors: Pattabiraman, Sundararaghavan, Azad, Gajendra Kumar, Amen, Triana, Brielle, Shlomi, Park, Jung Eun, Sze, Siu Kwan, Meshorer, Eran, Kaganovich, Daniel
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences; Cytoskeleton; Intermediate Filaments
• Online Access: https://hdl.handle.net/10356/146073
• Institution: Nanyang Technological University

Vimentin is one of the first cytoplasmic intermediate filaments to be expressed in mammalian cells during embryogenesis, but its role in cellular fitness has long been a mystery. Vimentin is acknowledged to play a role in cell stiffness, cell motility, and cytoplasmic organization, yet it is widely...