Topological analysis of protein structures with statistical learning

• Main Author: Lee, Si Xian
• Other Authors: PUN Chi Seng
• Format: Final Year Project
• Language: English
• Published: Nanyang Technological University 2021
• Subjects: Science::Biological sciences::Molecular biology; Engineering::Computer science and engineering::Computing methodologies::Artificial intelligence
• Online Access: https://hdl.handle.net/10356/146104
• Institution: Nanyang Technological University

The study of Protein structure-function relationship has been of key focus in computational biology. A novel method of protein data analysis involves the use of Persistent Homology Analysis (PHA) as a tool for protein classification. The main method of feature engineering from intervals generated is...