Serum albumin cysteine trioxidation is a potential oxidative stress biomarker of type 2 diabetes mellitus

• Main Authors: Paramasivan, Selvam, Adav, Sunil S., Ngan, SoFong Cam, Dalan, Rinkoo, Leow, Melvin Khee-Shing, Ho, Hee Hwa, Sze, Siu Kwan
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Biological sciences; Biomarkers; Mass Spectrometry
• Online Access: https://hdl.handle.net/10356/146114
• Institution: Nanyang Technological University

Metabolic disorders in T2DM generate multiple sources of free radicals and oxidative stress that accelerate nonenzymatic degenerative protein modifications (DPMs) such as protein oxidation, disrupt redox signaling and physiological function, and remain a major risk factor for clinical diabetic vascu...