Tumor‐microenvironment‐activated in situ self‐assembly of sequentially responsive biopolymer for targeted photodynamic therapy

• Main Authors: Wang, Xuan, Li, Menghuan, Hou, Yanhua, Li, Yanan, Yao, Xuemei, Xue, Chencheng, Fei, Yang, Xiang, Yang, Cai, Kaiyong, Zhao, Yanli, Luo, Zhong
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science::Medicine; Photodynamic Biopolymers; Self-assembly
• Online Access: https://hdl.handle.net/10356/146318
• Institution: Nanyang Technological University

A sequentially responsive photosensitizer-integrated biopolymer is developed for tumor-specific photodynamic therapy, which is capable of forming long-retained aggregates in situ inside tumor tissues. Specifically, the photosensitizer zinc phthalocyanine (ZnPc) is conjugated with polyethylene glycol...