Salt dependence conformational stability of the dimeric SAM domain of MAPKKK Ste11 from budding yeast : a native-state H/D exchange NMR Study

• Main Authors: Bhunia, Anirban, Ilyas, Humaira, Bhattacharjya, Surajit
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2021
• Subjects: Science; Protein Folding and Stability; SAM
• Online Access: https://hdl.handle.net/10356/146348
• Institution: Nanyang Technological University

The sterile α motif, also called the SAM domain, is known to form homo or heterocomplexes that modulate diverse biological functions through regulation of specific protein-protein interactions. The MAPK pathway of budding yeast Saccharomyces cerevisiae comprises a three-tier kinase system akin to ma...