Cinnamoyl sucrose esters as alpha glucosidase inhibitors for the treatment of diabetes

• Main Authors: Devaraj, Surabhi, Yip, Yew Mun, Panda, Parthasarathi, Ong, Li Lin, Wong, Kathy Pooi Wen, Zhang, Dawei, Judeh, Zaher
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2021
• Subjects: Engineering::Chemical engineering; Phenylpropanoid Sucrose Esters; Glycosides
• Online Access: https://hdl.handle.net/10356/146397
• Institution: Nanyang Technological University

Cinnamoyl sucrose esters (CSEs) were evaluated as AGIs and their enzyme inhibition activity and potency were compared with gold standard acarbose. The inhibition activity of the CSEs against α-glucosidase and α-amylase depended on their structure including the number of the cinnamoyl moieties, their...